Models to Study Colonisation and Colonisation Resistance

MRSA colonisation (eradicating colonisation in people without active/invasive infection).

INTRODUCTION Methicillin-resistant Staphylococcus aureus (MRSA) has a gene that makes it resistant to methicillin as well as to other beta-lactam antibiotics, including flucloxacillin, beta-lactam/beta-lactamase inhibitor combinations, cephalosporins, and carbapenems. MRSA can be part of the normal body flora (colonisation), especially in the nose, but it can cause infection. Until recently, MR...

Colonisation of the Land

The image of the colonisation of the land by plants as a spectacular event, when barren wastes suddenly became verdant triggered by a change in some extrinsic environmental factor, is fading. It derived from the appearance and rapid diversification of vascular plants, unequivocal land colonisers, and, almost simultaneously, the earliest terrestrial arthropods, in the late Silurian and early Dev...

Chronic colonisation with Pseudomonas

The cytokines interleukin-l and interleukin-2 participate in the inflammatory response, and may contribute to hypergammaglobulinaemia G and the development of lung injury in cystic fibrosis. Anti-inflammatory treatment with corticosteroids may attenuate this response. The effect ofa 12 week course of oral prednisolone on spirometry and serum concentrations of interleukin-la (IL-la), soluble int...

Can the Colonisation Resistance of the Oral Microflora be Enhanced?

INTRODUCTION The oral cavity offers a large number of shedding and non-shedding surfaces for colonisation. Initial colonisers tend to be aerobes or facultative anaerobes, relatively quick-growing, and able to adhere or be retained at a particular surface. Although many specific interactions are known between microorganisms and oral surfaces, there is an element of chance involved in which organ...

Friction zones in Lapita colonisation